Preserving the history of Andrews as a railroad and timber boomtown, the Andrews Train Depot is both a historic site and a working train stop on today's Amtrack Rail System. The Andrews Town Hall Museum features railroad memorabilia and a recreated Victorian Era home typical of 1909, when Andrews was founded.

Encompassing much of downtown Bennettsville, the Bennettsville Historic District includes historic homes, churches and public buildings. Among them is the Marlboro County Historic Museum and a historic home that was commandeered by Northern troops during the Civil War.

One of the earliest regions to be settled by English colonists, Britton's Neck and nearby Britton's Ferry was a center of Patriot sentiment during the American Revolution. The ferry that operated on the Pee Dee River was one of the first in northeastern South Carolina.

A towering riverside chimney is the sole reminder of a booming empire of timber and naval stores established here by a Northern timberman, Henry L. Buck, in the first half of the 19th century.

The oldest museum in the United States, the Charleston Museum was established in 1773. Its numerous exhibits, displays and artifacts survey South Carolina's rich history and culture.

Once the center of northeastern Marlboro County's cotton country, the small town of Clio offers drive-by visitors a remarkable collection of residential architectural styles from the late 19th and early 20th century.

Designed by the architect of the Washington Monument, the historic Conway City Hall building was built in 1825 as the Horry County Courthouse. Today, it is the central landmark for the historic river town of Conway which is one of the oldest towns in South Carolina. The picturesque Conway Riverwalk enables visitors to stroll alongside one of South Carolina's most scenic black-water rivers.

Located at Darlington Raceway, the Darlington Raceway Stock Car Museum features numerous exhibits associated with the history of NASCAR racing. Among the favorites are Richard Petty's famed Number 43 - 1967 blue Plymouth and Dale Earnhardt Senior's concrete handprints.

Considered to be the foremost architectural achievement of early 20th century architect William Augustus Edwards, the Dillon County Courthouse is a beaux-arts, brick and stone, Neoclassical structure known for its colossal central Ionic portico.

Located in Latta, the Dillon County Museum features a wide range of displays and artifacts related to local history, including a restored railroad caboose with a collection of railroad artifacts.

The Florence Railroad Museum, which is located on Irby Street beside the Florence City-County Government Complex, is housed in a restored railroad boxcar. The Museum features exhibits and artifacts related to the history of the railroad in Florence.

One of the region's earliest ferry-crossing sites, Galivants Ferry features a collection of historic structures from the 19th and early 20th centuries. It is also the site of the Galivants Ferry Stump Meeting, a Democrat Party political event that began with the 1876 election of former Confederate General Wade Hampton.

The third-oldest city in South Carolina, Georgetown is rich in history and culture, and offers visitors a wide variety of historic attractions from the Colonial Era to the present.

Located on historic Front Street in Georgetown, the Georgetown Rice Museum and the adjacent historic Kaminski Hardware Building present the history of the Georgetown-region rice empire.

The picturesque early 20th century courthouse was built in 1908 and features tree-shaded grounds, Greek-style columns and numerous monuments that are relevant to local history.

The Horry County Museum is located on Main Street, in downtown Conway, and features a variety of well-designed exhibits that chronicle the colorful history of Horry County. Permanent exhibits focus on local Native American culture, the timber industry and naval stores operations.

The final link of the famed 2,700 mile-long Intracoastal Waterway was completed in Horry County in 1936. Three historic bridges from the era may be viewed in Little River, at Pine Island, west of Myrtle Beach, and at Socastee.

The J.W. Dillon House Museum is the restored, early 20th century home of the founder of Dillon County, J.W. Dillon, a prominent local businessman who helped bring the railroad to Dillon County.